肺结核病人耐多药情况及防治策略分析

Analysis On Multi-drug Resistance Situation Of Lung Tuberculosis Patients And Its Control Measures

目的研究2008～2009年安徽省肺科医院肺结核病人耐多药及其治疗情况,为结核病防治提供依据。方法搜集相关资料,进行临床流行病学分析。结果在接受治疗的269例耐多药肺结核住院病人中,痰菌转阴、病灶吸收、空洞闭合和好转分别达到68.4%、79.9%、64.7%和85.1%。结论肺结核耐多药问题重在预防;制定合理有效的化疗方案,加强医防合作与管理,是防治肺结核病人耐药的有效途径。

Objective To study the multi-drug resistance situation and its treatment conditions of lung tuberculosis（TB） patients in Anhui Provincial Pulmonary Hospital from 2008 to 2009,and provide evidence for TB control and prevention.Methods Related materials were collected and analyzed by clinical epidemiological method.Results Among 269 cases of multi-drug resistant pulmonary tuberculosis（MDR-TB） inpatients in receiving treatment,the rate of sputum negative-transformation,focus absorbance,cavity closing and improvement were 68.4%,79.9%,64.7% and 85.1% respectively.Conclusion Prevention was the key for preventing multi-drug resistance.The effective ways to control and treat MDR-TB was to make a suitable,effective chemotherapy plan and strengthen the cooperation between hospital and prevention agencies.