脉血康胶囊联合低分子肝素钙(速碧林)治疗骨折术后下肢深静脉血栓形成的临床观察

Clinical observation of lower extremity deep venous hrombosis(DVT) postoperative fracture treated by Maixuekang capsule and low molecular heparin calcium(Subilin)

目的:观察脉血康胶囊联合低分子肝素钙(速碧林)治疗骨折术后下肢深静脉血栓形成的临床疗效。方法:对2008年2月至2010年4月214例骨折术后下肢深静脉血栓患者随机分为观察组和对照组,在综合治疗的基础上应用脉血康胶囊治疗下肢深静脉血栓107例。结果:观察组治愈及好转89例,无效18例;对照组治愈及好转66例,无效41例。观察组和对照组总有效率分别为83.18%和61.68%,2组疗效比较差异有统计学意义(P<0.05)。治疗后2组患、健肢周径有显著减少,血液流变学指标均有显著改善,2组间差异也有统计学意义(P<0.05)。结论:脉血康胶囊治疗下肢深静脉血栓有较好的疗效,联合低分子肝素钙(速碧林)治疗骨折术后下肢深静脉血栓形成,既有溶栓作用,又有抗凝作用,是个值得推荐的治疗方案。

Objective ： To observe the clinical curative effects of lower extremity deep venous thrombosis （DVT） postoperative fracture treated by Maixuekang capsule and low molecular heparin calcium （Subilin）. Method ： From Feb 2008 to Apr 2010,214 cases of lower extremity DVT postoperative fracture were randomly divided into experimental group and control group. The 107 cases of them were treated by Maixuekang capsule based on the comprehensive treatment. Result ： The 89 cases were cured and improved in the observation group, but 18 cases were ineffectiveness. The 66 cases were cured and improved in the control group, but 41 cases were ineffectiveness. Maixuekang capsule group had 83.18%（ 89/107） total effective rate and 61.68%（66/107） total effective rate in the control group. There was significant difference between the two groups （P〈0.05）. After the treatment, the perimeter between the suffered limb and the healthy one was significantly reduced, the blood rheology examination had been improved significantly. There was also significant difference between the two groups （P〈0.05）. Conclusion ： Maixuekang capsule for lower extremity deep vein thrombosis has good effect. It has both thrombolytic and anticoagulant effects for lower extremity DVT postoperative fracture treated by Maixuekang capsule and low molecular heparin calcium （Subilin）. It＇s a recommended treatment.