多囊卵巢综合征与代谢异常

Polycystic ovary syndrome and metabolic disturbances.

多囊卵巢综合征(PCOS)是生育年龄妇女常见的内分泌疾病,对女性的危害不只局限于对生殖功能的影响,而且可以导致患者糖、脂代谢异常,使得代谢综合征(MS)、2型糖尿病、心血管疾病的风险增加。PCOS患者的肥胖、胰岛素抵抗、高雄激素血症等是导致代谢异常的重要致病因素。重视对PCOS患者的早期管理,可以有效预防代谢异常发生及心血管疾病等的发生。

Polycystic ovary syndrome （PCOS）, a common endocrine disease among reproductive-aged women, imposed harmful effects not limited to the reproductive function, but also including higher risks for glucose intolerance, dyslipidemia,metabolic syndrome （MS） , type2 diabetes and cardiovascular diseases. Obesity, insulin resistance ,and hyperandrogenism in PCOS patients are the major pathogenic factors for these metabolic disturb- ances. Therefore, emphasis on early management of PCOS can be effective in preventing the occurrence of metabol- ic disturbances and cardiovascular diseases.