奥扎格雷钠联合低分子肝素钙治疗急性脑梗死68例疗效观察

Observation of clinical efficacy of ozagrel sodium combined with low molecular weight heparin calcium on 68 cases with acute cerebral infarction

目的探讨奥扎格雷钠联合低分子肝素钙治疗急性脑梗死的临床效果。方法选择我院急性脑梗死患者133例,将以上患者随机分为两组,观察组和对照组。两组患者均给予常规治疗。对照组患者给予血塞通,观察组患者给予低分子肝素钙和奥扎格雷。两组患者疗程为14 d。采用NIHSS对两组患者治疗前后进行神经功能缺损评分。结果观察组治疗后NIHSS评分与对照组比较,差异有统计学意义(P<0.05);观察组总有效率与对照组总有效率比较,差异有统计意义(P<0.05)。结论奥扎格雷钠联合低分子肝素钙能够显著改善急性脑梗死患者神经症状,临床效果显著,值得借鉴。

Objective To explore the clinical efficacy of ozagrel sodium combined with low molecular weight heparin calcium on acute cerebral infarction.Methods 133 cases with acute cerebral infarction were selected and divided into two groups,observation group and control group.The routine treatment was use to two groups,and xue sai tong injection was given to control group,ozagrel sodium combined with low molecular weight heparin calcium was used to observation group.the course was 14 days.the neurologic impairment score was detected by NIHSS before and after treatment.Results The scores of NIHSS in observation group compared with those in control group,there was statistical difference（P0.05）;the total effective rate of observation group compared with that of control group,there was statistical difference（P0.05）.Conclusion Ozagrel sodium combined with low molecular weight heparin calcium can improve the neural symptoms,and the clinical efficacy is significant,the therapy should be the reference for doctors.