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钙网蛋白与神经系统病变 被引量:1

Calreticulin and nervous system diseases
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摘要 钙网蛋白(calreticulin,CRT)是内质网中的一种多功能的分子伴侣,在协助蛋白质正确折叠和维持细胞Ca2+稳态(Ca2+信号)中发挥重要作用。近来的研究发现,钙网蛋白与神经系统病变包括阿尔茨海默氏病、帕金森病等有密切关系。 Calreticulin(CRT) is a kind of multi-functional protein in endoplasmic reticulum(ER),which plays important roles in a variety of cellular processes including Ca2+ signaling/ homeostasis and protein folding.Recent studies show that CRT is closely relevant with nervous system diseases,including Alzheimer's disease,Parkinson's disease.
作者 罗飞 柳长柏
出处 《生命科学》 CSCD 北大核心 2011年第3期283-285,共3页 Chinese Bulletin of Life Sciences
基金 湖北省教育厅自然科学研究重点项目(d200713004)
关键词 钙网蛋白 神经系统病变 阿尔茨海默氏病 帕金森病 calreticulin nervous system diseases Alzheimer's disease Parkinson's disease
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