10例存在气道高反应性过敏性鼻炎患儿的随访

Follow-up Analysis of Patients with Allergic Rhinitis associated with Airway Hyper-responsiveness

目的总结存在气道高反应性的过敏性鼻炎患儿的资料,分析与过敏性鼻炎预后的相关因素。方法选择过敏性鼻炎患儿10例,通过乙酰甲胆碱气道激发试验(MthBPT)诊断存在气道高反应性并予以鼻炎症状分级评分;24个月后再次行乙酰甲胆碱气道激发试验。结果 10例患儿中3例PD20值复诊时较初诊时降低。其中2例未用药,鼻炎症状分级评分由初诊时6分加重至复诊时8分;1例用药,鼻炎症状分级评分初诊时即高于8分并持续至复诊。结论症状严重、未接受药物治疗的过敏性鼻炎患儿气道高反应性有明显加重趋势。在考虑过敏性鼻炎诊断时,对患儿上、下呼吸道功能均应进行检查和评估。

Objective To analysis the follow-up results of children with allergic rhinitis （AR） associated with airway hyper-responsiveness （AHR）,and to analyze the clinical related factors for the prognosis of AR.Methods Ten children （age≥5 years old） who were diagnosed as AR duringJune,2005 to June,2006 in the E.N.T Dept.of the hospital of the Capital Institute of Pediatrics were examined by methacholine bronchial provocative test （Mth BPT） in order to confirm the diagnosed of AHR.The rhinitis syndromes were scored.Twenty-four months later,all ten children were followed up by repeated Mth BPT test.Results PD20 of three children were worse than before （two children with rhinitis symptom scored 6 at the first diagnosis,which became worse than before without drug administration.One child had persistent severe rhinitis syndrome even with drug administration.）.Conclusions Children with AR associated with severe rhinitis syndrome may become worsen without medicine administration/intervention.