橘红痰咳煎膏的质量标准研究

Quality Standard of Juhong Tanke Soft Extracts

目的:建立橘红痰咳煎膏的质量标准。方法:采用薄层色谱(TLC)法对橘红痰咳煎膏中茯苓、化橘红进行定性鉴别;采用高效液相色谱(HPLC)法测定橘红痰咳煎膏中的柚皮苷含量。结果:TLC斑点清晰,阴性对照无干扰;柚皮苷的进样量在0.163～0.816μg范围内与峰面积积分值呈良好线性关系(r=0.999 8),平均回收率为99.05%,RSD=1.8%(n=6)。结论:所建标准可有效控制橘红痰咳煎膏的质量。

OBJECTIVE：To establish the quality standard of Juhong tanke soft extracts.METHODS：Poria cocos and Citrus grandis in the prescription of Juhong tanke soft extracts were identified by TLC.The content of naringin was determined by HPLC.RESULTS：TLC spots were clear without interference from negative sample.The linear range of naringin was 0.163-0.816 μg（r=0.999 8） with an average recovery of 99.05%（RSD=1.8%,n=6）.CONCLUSION：Established standard can be used for the quality control of Juhong tanke soft extracts.