摘要
目的:本文联合应用纳诺酮、尿激酶及低分子肝素治疗35例急性脑梗塞(ACI)患者(治疗组),观察其治疗前后的β-内啡肽(β-EP)改变及临床疗效,方法:并与30例常规药物治疗组(对照组)比较。结果:结果显示,两组患者的血浆β-EP浓度均明显高于正常组,治疗组治疗后,其β-EP浓度显著下降,临床疗效明显高于对照组。提示纳络酮能明显降低(ACI)患者的血浆β-EP浓度。结论三药联合应用的临床疗效明显优于对照组。
objective:The treatment of 35 patients suffering from acute cerebrae infarction (ACI) using Naloxone, urokinase(Uk)and low molecular heparin(IMH)was observed (The treatment group), Methods: The treatment group was compared with 30 cases receiving only routine treatment (control group), Aftel treatment with medicine, the effect of treatment was observed, and β-endorphine(β-EP)was detected. Results:The resuks. showed that the levels of β-EP were significantly higher in treatment group and control group than those in normal subjects,The levels of β-EP were markedly lower in treatment group after treatment using Naloxone, Uk and IMH, and the effect of treatment was markedly higher than that of control group. Conclusion:We conclude that the levels of β-EP in treatment group can be decreased by using Naloxone, The effect of treatment using Mal oxone, Uk and IMH was obviously higher than that of using routine treatment.
出处
《重庆医学》
CAS
CSCD
1999年第5期339-340,共2页
Chongqing medicine
关键词
纳络酮
尿激酶
低分子肝素
脑梗塞
药物疗法
Acute cerebral infarction Naloxone Urokinase low-molecular haparin Effet of treatment