从痰瘀论治HAART致脂肪代谢障碍综合征

Treatment of LDs induced by HAART with a view of the phlegm and blood stasis in TCM

脂肪代谢障碍综合征是艾滋病患者使用抗逆转录病毒治疗后常见的副反应,它涉及脂肪重新分布和代谢障碍等内容,脂肪重新分布又包括脂肪沉积和脂肪萎缩两部分内容,代谢障碍即代谢综合征或X综合征主要指胰岛素抵抗、高血脂等。中医从痰、瘀角度来认识此病,气机郁滞、痰凝水聚、瘀血阻痹是主要病机变化过程,痰浊、瘀血贯穿在整个病理变化过程中。治疗当从祛痰化瘀、疏肝解郁、益气解毒之法,并注意顾护胃气。

Lipodystrophy syndrome is the common side effects of highly active anti-retroviral therapy,it is a broad term that refers to a variety of body shape changes and metabolic abnormalities,such as fat accumulation、lipoatrophy、insulin resistance,hyperlipidemia,etc.It can be understood that a state of the phlegm and blood stasis in TCM,the main pathogenesis of lipodystrophy syndrome is Qi stagnation,phlegm and blood stasis,the phlegm and blood stasis is the pathological changes throughout the process of the disease.The treatment should be activating blood and resolving stasis,soothing liver and relieving depression,tonifying qi and removing toxin and pay attention to nursing the Stomach-qi.