三联疗法治疗幽门螺杆菌相关性胃炎前后中医证型变化分析

Analysis of Changes in Traditional Chinese Medicine Types of Syndromes of Helicobacter Pylori-associated Gastritis before and after Triple Therapy

目的:通过观察幽门螺杆菌相关性胃炎(HPAG)患者在三联疗法治疗前后中医证型变化,探讨HPAG患者经标准三联治疗后中医证型的变化规律,指导中医药的后续治疗。方法:将符合纳入标准的HPAG患者按三联疗法标准方案予抗幽门螺杆菌(HP)治疗,7天为1个疗程。分别在治疗前、治疗后进行中医辨证分型。结果:HPAG患者经三联疗法治疗后,脾胃湿热证型较治疗前减少,脾胃虚弱证型较治疗前增多,其结果具有统计学意义。结论:HPAG患者经三联疗法治疗后中医证型发生了变化,具有从实证向虚证转变的规律,三联治疗疗法治疗后患者脾虚证型较治疗前增多。

Objective：Recearch the changes in traditional Chinese medicine types of syndromes of HPAG before and after triple therapy,analyze the influence of triple therapy to HPAG on traditional Chinese medicine types of syndromes,to guide the following Chinese medicine treatment.Methods：Through medical record material collection,we will conform to the HPAG patient which will bring into line with the standard.Treat according to the standard treatment,7 days for a course of treatment.Record patient＇s TCM syndrome type before and after the treatment.Results：Syndrome of spleen deficiencyhad significantly aggravated and syndrome of dampness-heat reduce after triple therapy,the results are statistically significant.Conclusion：Traditional Chinese medicine types of syndromes of HPAG had changed after triple therapy and the syndrome evolution regularity transfers from the excess syndrome to the deficiency syndrome.Syndrome of spleen deficiency had significantly aggravated after triple therapy.