四种化学预备液对根管壁显微硬度的影响

Effects of Four Chemical Fluids on Root Dentine Microhardness of Human Teeth.

目的:评价乙二胺四乙酸盐(ethylenediamine tetraacetic acid,EDTA)、氯亚明(Chloramine)、丁克除(Des-occlusol)和酚克除(Resosolv)4种化学预备液根管内封药时对根管壁显微硬度的影响。方法:选择因正畸拔除的健康前磨牙65颗,实验组60颗和对照组5颗。实验组随机分为A、B、C、D 4组,每组15颗,各组又随机分为10 d组、20 d组和30 d组,每组5颗。常规开髓、拔髓、干燥根管后丙烯酸树脂封闭根尖孔。根管内封药,磷酸锌暂封,4℃储存,对照组不做任何处理,相同条件下储存。丙烯酸树脂包埋,硬组织切片机切片,显微硬度仪进行硬度测试,数据进行方差分析。结果:在本实验周期内,与正常对照组相比较,EDTA封药10 d和20 d组,根管壁的显微硬度下降无统计学意义;封药30 d组,根管壁的显微硬度下降有统计学意义(P<0.05)。氯亚明,丁克除和酚克除封药3个时间组,根管壁的显微硬度下降均无统计学意义。结论:在本实验周期内,EDTA封药10 d和20 d组,对根管壁的显微硬度无明显影响,而封药30 d组,对根管壁的显微硬度有显著影响。氯亚明、丁克除和酚克除3个封药时间组对根管壁的显微硬度均无明显影响。

Objective： To evaluate the effects of EDTA,Desocclusol,Resosolv and Chloramine on the microhardness of human root canal dentine at three different time points.Methods： Sixty-five human healthy premolars were randomly divided into tow groups： the experiment group with sixty pills and the control group with five pills.The experiment group was randomly divided into four groups of 15 discs each.They were put the cotton twist filled with the four fluids into the root canal after opening and extirpation of pulp,then depoted in normal saline at the condition of four centidegree.The cotton wool was after removed 10days,20 days and 30days.Then,both the experiment group and the control group were embedded,affixed and cutsheeted before hardness test.Results： The results were analyzed using one-way ANOVA.EDTA produced a significantly grater reduction in microhardness after 30 days but not 10 days or 20 days.Chloramine,Desocclusol and Resosolv produced no significant difference at three different timepoints.Conclusion： It is safety for EDTA to leave in root canal for 20 days,and Chloramine,Desocclusol and Resosolv for 30 days,wich would not lead to a significant microhardness reduction.