体质学说对中医药治疗幽门螺杆菌感染的启示

Treatment of Helicobacter pylori infection by Chinese medicine:what we can learn from the physical constitution theory?

由于抗生素的普遍使用,幽门螺杆菌(H.pylori)感染的治疗除副作用外,耐药、变异及再感染等问题应引起重视和深思.中医药治疗H.pylori有一定优势,但根除率低,体质研究的开展为我们提供了新思路.本文认为脾胃是体质形成发展的基础,与H.pylori感染的发生密切相关,体质决定了H.pylori感染后的发病、预后及证候转化转归,启示对H.pylori感染的治疗,不能囿于"根除"及"见菌治菌"的论治思路,结合体质的可调性,通过邪正祛邪,辨证辨病结合辨体论治,有助于发挥中医药特色,提高疗效.

The widespread use of antibiotics has been linked to the development of resistance to antibiotics,bacterial variation and re-infection in the treatment of Helicobacter pylori（H.pylori）infection.Treatment of H.pylori infection by Chinese medicine possesses some advantages but has a low eradication rate.The research on the physical constitution provides us some new ideas.Spleen and Stomach are the foundation of physical constitution.H.pylori infection is closely related to the physical constitution of patients,and the physical constitution determines the development,syndrome transformation and prognosis of H.pylori infection.Treatment of H.pylori infection should not be limited to ＂eradication＂ or ＂killing bacteria once it was detected＂.Due to the adjustability of the physical constitution,H.pylori infection can be treated by enhancing vital Qi and dispelling evil on the basis of syndrome differentiation,disease differentiation and constitution differentiation.