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缺血性结肠炎研究现状 被引量:8

Current Status of Study on lschemic Colitis
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摘要 缺血性结肠炎(IC)是缺血性肠病中最常见的类型,人群发病率为(4.5~9.9)/10万人年,老年人高发,女性患者相对多见.临床表现主要为左下腹痛、血性腹泻和便血,症状轻重与缺血程度有关,多数为轻度黏膜或黏膜下损伤引起的短暂可逆性症状,少数表现为急性暴发性缺血伴透壁性梗死,可进展至结肠坏死甚至致死.IC常与心血管疾病、缩血管药物的使用、腹部血管手术、肠易激综合征、便秘等有关. Ischemic colitis (IC) is the most common type of ischemic bowel diseases. Its incidence in general population ranges from 4.5 to 9.9 cases per 100 000 person-years. IC typically affects elderly patients and females. Patients with IC usually experience lower left abdominal pain, along with bloody diarrhea and hematochezia. The severity of symptoms depends on the degree of ischemia. Most patients have transient, reversible ischemia involving the mucosa and submucosa. Some patients manifest acute fulminant ischemia associated with transmural infarction that may progress to necrosis and even being fatal. The risk factors include cardiovascular disease, use of vasoconstrictor, abdominal vascular surgery, irritable bowel syndrome, and constipation, etc.
作者 沈峰 范建高
出处 《胃肠病学》 2010年第12期764-766,共3页 Chinese Journal of Gastroenterology
关键词 结肠炎 缺血性 流行病学 体征和症状 治疗 预后 Colitis, Ischemic Epidemiology Signs and Symptoms Therapy Prognosis
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