La对纯钛微弧氧化膜层的组织结构及细胞相容性的影响

Effects of La on microstructures and biocompatibility of pure Ti micro-arc oxidation coatings

在乙酸钙-磷酸二氢钙电解液中添加硝酸镧,对纯钛进行微弧氧化处理,利用XRD、SEM和EDX分别研究了La元素对膜层形貌、成分、物相的影响及作用机制,并利用细胞接种方法研究膜层的生物活性。结果表明:电解液中添加La降低膜层厚度,增加膜层孔洞尺寸,抑制锐钛矿向金红石型转变,并在微弧氧化过程中具有促进羟基磷灰石HA形成的能力。煅烧处理使膜层中的非晶HA晶化,形成片状和鳞状的HA晶体;膜层经煅烧后形成的HA/TiO2复合膜具有良好的细胞相容性。

Ca（CH3COO）2·H2O-Ca（H2PO4）·H2O electrolyte system with La（NO3）3·6H2O was used to carry out micro-arc oxidation treatment on pure titanium. By means of XRD,SEM and EDX,the effects of La on morphologies,phases and compositions of coatings gained from the electrolyte were investigated. The cell culture method was used to study the cyto-compatibility of the coating. The results show that the coatings formed in electrolyte with La are thinner and have larger pores than those formed in electrolyte without La. Addition of La can inhibit the transition from anatase to rutile and has stronger capability of inducing HA. After being sintered,the amorphous hydroxyapatite （HA） in coatings is crystallized into flake or scaly. The new coatings after being sintered with HA/TiO2 are proved to have good biocompatibility.