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Event-related potential N170 for early diagnosis of face recognition impairment in Parkinson's disease

Event-related potential N170 for early diagnosis of face recognition impairment in Parkinson's disease
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摘要 Event-related potential (ERP) studies of cognitive function in Parkinson's disease (PD) have focused on P300 and N270. However, little is known regarding face recognition ERP in PD. The present study assessed cognitive function in PD patients using neuropsychological scales and analyzed N170 of visuospatial function impairment (VFI) in PD. Results showed that Montreal cognitive assessment can be used for assessing cognitive impairment when visuospatial functioning is changed during the early stage of PD. Face recognition has clinical significance for detecting changes in visuospatial functioning. However, N170 is not sensitive for detection of VFI in PD, which implies that VFI does not appear in the stage of structure coding in face recognition. In addition, VFI affects face recognition. Event-related potential (ERP) studies of cognitive function in Parkinson's disease (PD) have focused on P300 and N270. However, little is known regarding face recognition ERP in PD. The present study assessed cognitive function in PD patients using neuropsychological scales and analyzed N170 of visuospatial function impairment (VFI) in PD. Results showed that Montreal cognitive assessment can be used for assessing cognitive impairment when visuospatial functioning is changed during the early stage of PD. Face recognition has clinical significance for detecting changes in visuospatial functioning. However, N170 is not sensitive for detection of VFI in PD, which implies that VFI does not appear in the stage of structure coding in face recognition. In addition, VFI affects face recognition.
出处 《Neural Regeneration Research》 SCIE CAS CSCD 2010年第24期1845-1850,共6页 中国神经再生研究(英文版)
关键词 Parkinson's disease visuospatial function impairment face recognition event-related potential Parkinson's disease visuospatial function impairment face recognition event-related potential
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