烧伤早期氧化损伤与抗氧化治疗

Oxidative injury and antioxidant therapy in early stage of burn

严重烧伤早期由液体丢失及液体复苏而造成的缺血-再灌注损伤,以及应激而发生的神经、体液变化可使机体发生严重的氧化损伤,是导致多器官损伤的重要机制之一。文章就严重烧伤后活性氧对机体的氧化损伤及抗氧化治疗的研究进展作一综述。

In the early stage of severe burn,ischemia-reperfusion injury caused by fluid loss and fluid resuscitation and changes in nerve and body fluid caused by stress may lead to severe oxidative damage,which is one of the important mechanisms of multiple organ injury.The research progress of oxidative injury from reactive oxygen species and antioxidant therapy in the early stage of severe burn is reviewed in this paper. 更多还原