腹腔海水浸泡并淹溺时对犬血浆电解质的影响

Changes in serum electrolyte levels after seawater immersion of open abdominal wound and drowning in dogs

目的了解犬腹部开放伤后海水浸泡并淹溺时对其机体电解质水平的影响。方法实验动物致伤后随机分为对照组、海水浸泡组和海水浸泡并淹溺组,每组7只。对照组为单纯腹外伤,后两组动物致伤后置于海水浸泡,其中淹溺组给予气管中灌注海水,观察各组动物外周血钠、钾、氯水平及渗透压的变化。结果和结论腹腔海水浸泡可导致犬高钠血症、高钾血症、高氯血症及高渗透性脱水,腹腔海水浸泡后气管灌注海水对血浆电解质的影响不明显,血浆电解质影响度随腹腔浸泡时间延长而加大。

Objective To assess the effects of seawater immersion of open abdominal wound and drowning on plasma electrolyte levels in dogs.Methods Twenty-one dogs with open abdominal wounds were randomly divided into 3 groups,namely the control group（n=7）,seawater immersion group（n=7） and seawater immersion and drowning group（n=7）.The dogs in the control group were subjected to simple open abdominal wound,and those in the latter two groups were immersed into seawater after the abdominal injury.The changes in the plasma electrolytes and osmotic pressure were observed after the treatments.Results and Conclusion Seawater immersion of the open abdominal wound results in hypematremia,hyperkalemia and hypertomic dehydration,and the effect is proportional to the length of immersion time,but seawater airway perfusion does not cause obvious changes of the plasma electrolytes and osmotic pressure in dogs.