一例患腹泻症藏酋猴继发感染病例病理学观察

Pathological Observation on Macaca speciose thibetanas with Secondary Infection Caused by Diarrhea

目的 为探明患腹泻症藏酋猴继发感染病例的致病机理.方法 对一例曾有反复腹泻病史的8岁龄藏酋猴进行病理学研究.结果 临床症状上,该猴处于严重脱水状态;大体解剖上,该猴的肺部和小肠均出现严重眼观病变;组织病理学上,该猴的肝脏、肾脏组织均出现颗粒变性和空泡变性,多组织器官性的血管发生淤血、充血,管壁间质发生水肿;胰腺、膀胱和脑部组织均未见异常组织病变.结论 猕猴的腹泻具有病因复杂和季节性发生的特点,治疗应坚持中草药治疗为主,西药治疗为辅的原则.

Objective To probe etiopathogenesis of secondary infection caused by diarrhea in one Macaca speciose thibetanas. Methods The pathological observation on an 8 year-old Macaca speciose thibetanas with historically recurring diarrhea were carded out. Results The Macaca speciose thibetanas was in the the dehydrant condition as showed in the clinical symptom. Also serious pathologyical change was observed in the lung and intestine. Histopathologically, granular degeneration and vacuolar degeneration were observed in the liver and kidneys. Congestion and hyperemia were observed in the blood vessel of many tissues and organization, and the inervallum of vessel wall was swollen. Pancreas, bladder and brain were normal. Conclusion The characters of diarrhea in Macaca speciose thibetanas are complex etiological factors and seasonal occurrence. The treatments on diarrhea of such animal are suggested to mainly depend on TCM and modem treatments to be adjuvant.