一种衣物消毒液的性能观察

OBSERVATION ON THE PERFORMANCE OF A CLOTHING DISINFECTANT

目的观察一种衣物消毒液的消毒相关性能。方法采用悬液定量杀菌试验和理化试验方法,对该衣物消毒液杀菌效果、毒性和理化性能进行了实验室和现场试验。结果以含醋酸氯己定566 mg/L该衣物消毒液作用5min,对悬液内金黄色葡萄球菌和大肠杆菌平均杀灭对数值均为5.0以上;作用10 min,对悬液内白色念珠菌平均杀灭对数值为4.0以上。用上述浓度的该衣物消毒液对纺织品浸泡作用10 min,对自然菌平均杀灭对数值达到1.0以上。该衣物消毒液对小鼠经口急性毒性LD50值>5 000 mg/kg(体重),无致微核作用。将该衣物消毒液密封包装置37℃储存90 d,其醋酸氯己定含量下降率均值小于1.50%。结论该衣物消毒液储存性能稳定,对细菌繁殖体和真菌杀灭效果较好,属基本无毒级物质。

Objective To observe the disinfection performance of a clothing disinfectant. Methods Suspension quantitative germicidal test and physical and chemical test were used to observe the bactericidal effect,toxicity and physical and chemical properties of clothing disinfectant. Results The average killing logarithm values of Staphylococcus aureus and Escherichia coli in suspension exposed to disinfectant containing chlorhexidine acetate 566 mg/L for 5 min were 5.0;that of Candida albicans exposed to disinfectant containing 566 mg/L chlorhexidine acetate for 10 min was 4.0.The average killing logarithm value of natural bacteria on textile soaked in clothing disinfectant of this concentration for 10 min was 1.0.The mouse acute toxicity test for this clothing disinfectant indicated that the oral LD50 was 5 000 mg/kg and the result of micronucleus test was negative.The decrease rate of chlorhexidine acetate concentration was 1.50% when this disinfectant stored at 37℃ for 90 d with sealed bag. Conclusion The clothing disinfectant solution is stable and has good germicidal efficacy on vegetative form of bacteria and fungi.It has no toxicity basically.