摘要
目的:总结我院2007年~2010年6月药品不良反应监测情况,促进临床安全、合理用药。方法:采用描述性研究的方法,对我院上报的药品不良反应分别从患者的基本情况、给药途径、联合用药、临床表现等方面进行统计、分析与评价。结果:358例不良反应监测报告中,患儿年龄0~3岁169例,占47.20%;与抗菌药物有关的327例,占91.34%,其中β内酰胺类296例,β内酰胺类引起的ADR多为皮疹、荨麻疹、过敏样反应;以静脉滴注途径给药的发生频率最高,共298例占83.24%。结论:我院婴幼儿抗菌药物静脉注射时发生的不良反应较多,应予以重点关注。
Objective: To summarize the results of adverse drug reaction supervision in our hospital from January in 2007 to June in 2010 in order to improve rational and safe clinical drug treatment for children.Methods: Methods of descriptive study,statistics and analysis were used to estimate some characteristics of medicine usage.This included patients' basic conditions,route of administration,drug combination and clinic manifestations.Results: Among 358 reports about adverse drug reactions,there were 169 cases aged between 0 and 3 years,which accounted for 47.2%.There were 327 cases relating to the use of antibiotics,taking up 91.34%,in which there were 296 cases relating to β-lactam antibiotics.The most usual adverse drug reaction caused by β-lactam antibiotics were skin rashes,urticaria and anaphylactoid reactions.Among those 358 cases,adverse drug reaction occurred more easily when administrated via intravenous dropping method,which accounted for 83.24%(298 cases).Conclusions: There are more adverse drug reactions taking place in neonates and children when antibiotics are administrated by intravenous dropping method.This method of treatment needs to be further studied.
出处
《儿科药学杂志》
CAS
2011年第2期39-41,共3页
Journal of Pediatric Pharmacy
关键词
儿童
药品
不良反应
Children
Drug
Adverse drug reaction