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家兔的甲型H_1N_1流感病毒裂解疫苗应答抗体检测

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摘要 用甲型H1N1流感病毒裂解疫苗(甲流疫苗)对家兔进行两次免疫[1],采集家兔免疫前、初次免疫后第15天和加强免疫后第15天血清,用血凝抑制试验和中和试验检测其血清抗体[2]。结果证明家兔初次免疫后其血清抗体效价不高,
出处 《浙江预防医学》 2011年第4期36-37,共2页 Zhejiang Journal of Preventive Medicine
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  • 1WHO. Cumulative number of confirmed human cases of avian influenza A/ ( HsN1 ) reported to WHO [ EB/OL]. (2008 -04 -15) [2008-04-18]. http: www. who. int/csr/disease/ avian_ influenza/country/cases table_ 2008_ 04_ 15/en/ index, html.
  • 2WHO. Availability of HsNt prototype strains for influenza pandemic vaccine development [EB/OL]. (2005-02) [2008-04-18]. http: www. who. int/csr/diseasJavian influenza/guidelines/ avian influenza_ prototype_ straina/en/index, html.
  • 3WHO. Availability of new recombinant H5N1 vaccine vires [ EB/ OL]. (2006-12-21)[2008-04-183. http: www. who. int/csr/disease/avian influenza/guidelines/5 Nl vaccinevirus/en/ index, html.
  • 4FDA. FDA approves first U. S. vaccine for humans against the avian influenza virus H5Nl [ EB/OL ]. ( 2007 - 04 - 17 ) [2008 -04 - 18]. http: //www. fda. gov/bbs/topica/NEWS/ 2007/NEW01611. html.
  • 5Gao W, Doloff AC, Lu X, et al. Protection of mice and poultry from lethal HsN1 avian influenza virus through adenovirusbased immunization [J]. Virol, 2006, 80 (4): 1959-1964.

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