补体溶菌试验检测血清杀弧菌抗体

The Detection of Vibriocidal Antibody in Serum by Complment Bacteriolysis Test

目的：评估血清杀霍乱弧菌抗体的检测对霍乱和流行病学调查的价值。方法：对３０ 例霍乱病人和３０ 例正常人的血清，采用补体溶菌试验检测血清中抗体滴度的变化。结果：试验组几何平均滴度１∶８９；对照组几何平均滴度１∶２．４，差异有非常显著的意义（ｔ＝ １１．２，Ｐ＜ ０．００１）。结论：该试验敏感、特异、操作简单、结果易判断，有一定的实用性。

Objective:To evaluate the value of cholera diagnosis and epidemioloy investigation by detecting vibriocidal antibody in serum.Methods:To detect antibody titer both 30 patients with cholera and 30 controls by complment bacteriolysis test.Results:The geometric mean titer of antibody in patients was 1∶89;The geometric mean titer in centrols was 1∶2.4 There was a higher significant difference( P <0.001).Conclusion:This test is sensitive,specific,easy and accurate.It was practical.