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Carbon Nanotube-hybridized Supramolecular Hydrogel Based on PEG-b-PDMAEMA/α-cyclodextrin

Carbon Nanotube-hybridized Supramolecular Hydrogel Based on PEG-b-PDMAEMA/α-cyclodextrin
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摘要 Well-dispersed multi-walled cabon nanotubes(MWCNTs) were successfully incorporated into a supramolecular hydrogel through combining dual roles of poly(ethylene glycol)-block-poly[(2-dimethylamino) ethyl methacrylate](PEG-b-PDMAEMA) copolymer in dispersing MWCNTs and forming inclusion complexes with α-cyclodextrin(α-CD).Rheological behaviors of supramolecular hydrogels were investigated.The resultant hybrid hydrogels were found to be shear thinning and could be applied as a promising injectable drug delivery system.The mechanical strength of the hybrid hydrogels was greatly improved in comparison with that of the corresponding native hydrogels. Well-dispersed multi-walled cabon nanotubes (MWCNTs) were successfully incorporated into a supramolecular hydrogel through combining dual roles of poly (ethylene glycol)-block-poly [(2-dimethylamino) ethyl methacrylate] (PEG-b-PDMAEMA) copolymer in dispersing MWCNTs and forming inclusion complexes with α-cyclodextrin (α-CD). Rheologicai behaviors of supramolecular hydrogels were investigated. The resultant hybrid hydrogels were found to be shear thinning and could be applied as a promising injectable drug delivery system. The mechanical strength of the hybrid hydrogels was greatly improved in comparison with that of the corresponding native hydrogels.
出处 《科技信息》 2011年第5期I0168-I0168,I0419,共2页 Science & Technology Information
关键词 碳纳米管 超分子水凝胶 药物输送系统 机械强度 Hybrid hydrogel MWCNTs PEG-b-PDMAEMA α-CD Rheology
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