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宫颈疾病液基细胞学与病理学组织学检查结果对照分析

Comparative Study between Liquid-based Cytology and Pathology in Cervical Diseases
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摘要 目的:评价液基细胞学诊断结果与病理组织学检查结果的阳性符合率及其在宫颈良恶性病变诊断中的应用价值。方法:对液基细胞涂片诊断阳性(ASC以上)并追踪到确切组织学诊断的282例患者的细胞学与组织学诊断结果进行对照分析。结果:282例中细胞学诊断癌35例,高度鳞状上皮内病变(HSIL)44例,低度鳞状上皮内病变(LSIL)84例,非典型鳞状细胞(ASC)99例,非典型腺细胞(AGC)20例,与组织学结果对照,阳性符合率分别为:癌90.2%,HSIL 83.0%,LSIL71.8%。11例ASC中3例HSIL,3例LSIL;20例AGC中腺癌2例,鳞癌1例;CINⅢ级累及腺体2例,CINⅠ级4例,内膜增生过长4例。结论:液基细胞学有助于癌、宫颈上皮内瘤变的检出及细胞学诊断阳性符合率的提高;2001版TBS系统对ASC的分类有助于临床医师对患者的管理;AGC患者宫颈和颈管细胞学检查阴性时,内膜诊刮是必要的。 Objective:To assess positive accurate rate and application in the results of diagnosis of liquid-based cytology(TCT) and pathology in cervical diseases.Methods:282 of 487 positive TCT samples were eligible for pathological assessment in this study.And comparison between TCT and histopathology was conducted retrospectively.Results:35,44,84,99 and 20 of 282 cases had cancer,high-grade intraepithelial lesion(HSIL),low-grade intraepithelial lesion(LSIL),atypical squamous cell(ASC) and atypical squamous cell(AGC) respectively,as well as 90.2 % in cancer,83.0 % in HSIL,71.8 % in LSIL in pathological diagnosis.Conclusion:TCT examination is in favor of diagnosis in cervical cancer and cervical intraepithelial neoplasia(CIN),it can improve the positive accurate rate of TCT.Other than endometrial diagnosis is necessary,if examination of cervix and neck tube cytology shows negative.
作者 张易青
出处 《青海医药杂志》 2011年第2期8-11,共4页 Qinghai Medical Journal
关键词 液基细胞学 宫颈上皮内瘤样病变 腺癌 TBS Liquid-based cytology Cervial intraepithelial nesplasm Pathology Cancer
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参考文献10

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