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烟浪丁片剂储存稳定性实验研究

Studies on the Storing Stability of the Nicorandil Tablet
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摘要 对烟浪丁片剂储存过程中的药物含量进行了追踪检测。结果表明,该制剂在存储过程发生了不同程度的分解,对存放 24 个月左右的药片,测定的标示含量仅是设计含量的一半。 It was timely tested by chemical analysis that the content of N-(2-hydroxyethyl) nicotinamide nitrate in the Nicorandil tablet during the storing. It was found that the N-(2-hydroxyethyl) nicotinamide nitrate in the tablet had decomposed differentlly in the storage and the content tested is half designation number after about two years storing. The decomposing mechanism of the medicine was also discussed in this paper.
作者 陈莉英
出处 《陕西化工》 CSCD 1999年第3期24-25,共2页 Applied Chemical Industry
关键词 烟酰胺硝酸酯 烟浪丁片剂 储存稳定性 冠心病药 N-(2-hydroxyethyl) nicotinamide nitrate nicorandil tablet storing stability
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参考文献3

  • 1戴诗文 许景峰.抗心绞痛新药--烟浪丁[J].新药与临床,1985,4(4):34-35.
  • 2许景峰 宋颖 等.烟浪丁的酰氯法合成[J].医药工业,1984,(4):34-34.
  • 3刑为凡 张效联 等.抗高血压新药烟浪丁的合成[J].医药工业,1983,(11):2-3.

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