银杏达莫联合尼莫地平治疗血管性痴呆的疗效观察

Observation of Curative Effect of Yinxingdamo Combined with Nimodipine on Vascular Dem Entia of Elderly Patients

目的:研究银杏达莫联合尼莫地平治疗血管性痴呆(VD)的疗效。方法:患者随机分为两组,尼莫地平为对照组,观察组银杏达莫联合尼莫地平。治疗前后测定简易智力状态检查量表(MMSE)、日常生活能力量表(ADL)、神经功能缺损评分(NDS)。结果:治疗组有效率为86.7%,对照组有效率为66.7%,2组比较差异有统计学意义(P<0.05)。MMSE积分明显升高,ADL测定、NDS评分较治疗前明显降低,均有统计学差异(P<0.05)。结论:银杏达莫联合尼莫地平可明显改善VD患者认知功能障碍和日常生活能力,促进神经功能康复。疗效优于单用尼莫地平。

Objective： To investigate the curative effect of yinxingdamo combined with N imodipine on vascular dementia of elderly patients.Methods：60 elderly patients with vasculardementiawere randomly selected and divided into 2 groups. 30 cases in the control group were treated with Nimodipine, while 30 cases in treatment group were treated with yinxingdamo combined with Nimodipine. The score was detected before and after treantments according to the MMSE,ADL and NDS. Results：The MMSE score increased obviously and the ADL and NDS score decreased in treatment group after teatments,have statistical significance （P〈0.05 or P〈0.01）.The total efficiency in treatment group was 86. 7% versus 66. 7% in control group（P〈0.01）.Conclusions：Compared with Nimodipine, yinxingdamo combined with Nimodipine has a better effecton vasculardementia of elderly patients.