血清脂蛋白(a)在高血压肾病诊断中的意义

Serum Lipoprotein-a in the Diagnosis of Hypertensive Nephropathy

目的:对高血压肾病患者诊断过程中检测血清脂蛋白(a)的意义进行探讨。方法:按照有无肾病,将224例患者分为3组:1组76例,高血压无肾病,2组76例,高血压肾病微量蛋白尿,3组72例,高血压肾病大量蛋白尿。采用免疫比浊法,对患者血清脂蛋白(a)测定,比较血清脂蛋白-a的规律。结果:和高血压无肾病患者对比,高血压肾病微量蛋白尿患者和高血压肾病大量蛋白尿患者血清脂蛋白(a)升高明显,差异有统计学意义(P<0.05)。结论:血清脂蛋白(a)量和尿蛋白的量正相关,这显示血清脂蛋白(a)的含量对高血压肾病的诊断具有重要意义。

Objective：The diagnostic process in patients with hypertensive nephropathy serum lipoprotein-a in the sense discussed. Methods：According to whether the kidney will be 224 cases were divided into 3 groups：The first group of 76 patients with hypertension without kidney disease,the second group of 76 patients,hypertensive nephropathy microalbuminuria,the third group of 72 patients,hypertensive nephropathy pee a lot Protein.By immunoturbidimetric assay for determination of serum lipoprotein-a,comparison of serum lipoprotein-a rule. Results：Comparison of patients without nephropathy and high blood pressure,hypertension,microalbuminuria in patients with kidney disease and hypertension in patients with kidney disease a lot of protein in urine increased significantly in serum lipoprotein-a,the difference was statistically significant （P〈0.05）.Conclusion：Serum lipoprotein-a volume and the amount of urinary protein positive correlation, indicating that the content of serum lipoprotein-a diagnosis of hypertensive nephropathy is important.