晚期非小细胞肺癌伴恶性胸腔积液的双介入治疗探讨

The double interventional therapy of advanced non-small cell lung carcinoma and malignant pleural effusion

目的：评价选择性支气管动脉灌注化疗问AI）和胸腔内灌注化疗（Pll）联合治疗晚期非小细胞肺癌（NSCDe）伴恶性胸腔积液（MPE）的疗效。材料和方法：30例病变局限于胸部的晚期NSCLC伴MPE患者。先经BAI治疗2－7天再行PLI。结果：肺部原发灶有效率86．7％，MPE有效率93．3％，6个月、1年、2年生存率分别为对．3％、63．3％、30％。结论：BAI和PLI联合治疗晚期NSCLC伴MPE安全有效，先用BAI，后用PLI，效果较好。

Objective:To evaluate the effect of the combinational therapy of bronchial artery infusion(BAI)and pleural transluminal infusion(PLI)of advanced non-small cell lung carcinoma(NSCLC)with malignant pleural efffusin (MPE).Materials and Methods:Thirty patients with advanced NSCLC and MPE (Tumor only in chest)were treated with PLI 2-7days after treated with BAI.Results:Efficiency of treatment of tumor in lungs or MPE was 86.7% or 93.3% respectively.The survival rate of 6 months,1 year or 2 years was 93.3%,63.3% or 30% respectively.Conclusion:It is an effective therapy in treatment of advanced NSCLC with MPE with combination of BAI and PLI.