1Walter HJ, Berry M, Hill DJ, et al. Sptial and temporal changes in the insulin-like growth factor (IGF) axis indicate autocrine/paracrine action of IGF- 1 within wounds of the brain. Endocrinology, 1997,138970:3024
2Beeton CA, Brooks RA, Rushton N. Circulating levels of insulin-like growth factor- 1 and insulin-like growth factor binding protein - 3 in patients with severe head injury. J Bone Joint Surg (Br), 2002, 84(3): 439
3Ross R, Miell J, Freeman E, et al. Critically ill patients have high basal growth hormone levels with attenuated oscillatory activity associated with low levels of insulin-like growth factor - 1. Clin Endocrinol,1991, 35:47
4Wildburger R, Zarkovic N, Leb G, et al. Post-traumatic changes in insulin-like growth factor type 1 and growth hormone in patients with bone fractues and traumatic brain injury. Wien Klin Wochenschr, 2001, 113 (3～4): 119
5Klein BY, Shohami E, Reikhinshtein Y. Serum-mediated osteogenic effects of head injury on cultured rat marrow stromal cells. Calcif Tissue Int, 1999, 65 (3): 217
6Perkin SR, Skirving AP. Callus formation and the rate of healing of femoral fractures in patients with head injuries. J Bone Joint Surg (Br), 1987, 69 (4): 521
7Spencer RF. The effect of head injury on fracture healing. J Bone Joint Surg (Br), 1987, 69 (4): 525
8Bidner SM, Rubin IM. Evidence for a humoral mechanism for enhancedosteogenesis. J Bone Joint Surg (Am), 1990, 72 (8):1144
9Malcangio M, Garrett NE. Nerve growth factor freafment increases stimulus-evoked release of sensory neuropeptides in the rat spinal cord.EurJ Neurosci, 1997, 9 (5): 1101
7Marmarou A. A new model of diffuse brain injury in rats. Pathophysiology and biomechanics. J Neurosurg. 1994;80(2) 301-313.
8Roberts JM. Multiple injuries: management of the patient with a fractured femur and a head injury. J Bone Joint Surg. 1968; 42(3):425.
9Boes M, Kain M, Kakar S, et al. Osteogenic effects of traumatic brain injury on experimental fracture-healing. J Bone Joint Surg Am. 2006;88(4):738-743.
10Zwerina J, Redlich K, Polzer K, et al. TNF- induced structural Joint Damage is mediated by IL-I. Proc Natl Acad Sci USA. 2007;104(28):11742-11747.
