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API5相关的研究进展 被引量:1

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摘要 细胞凋亡的级联反应在正常的病理过程中是受严格控制的,在某种程度上是由API5所调控。API5(Apoptosisinhibitor 5)是一种细胞凋亡抑制蛋白。API5是E2F1诱导细胞凋亡强有力的抑制剂。研究表明NDRG2与API5相互作用,NDRG2调控API5可能会降低肿瘤细胞的生存能力;miR-224能负调控API5的表达;API5可能会成为可利用的抗肿瘤的治疗靶点。
出处 《安徽农学通报》 2011年第7期46-46,77,共2页 Anhui Agricultural Science Bulletin
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