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X-连锁无丙种球蛋白血症并幼年特发性关节炎四例 被引量:6

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摘要 X-连锁无丙种球蛋白血症(XLA)是一种遗传性体液免疫缺陷病,其临床表现除反复、严重的细菌感染外,部分患者合并自身免疫性疾病,发生率最高的为幼年特发性关节炎(JIA)。经合理治疗,其预后及转归良好,但须强调治疗的个体化和特殊性。现总结我院1999年至2009年收治的4例XLA合并JIA患儿的临床资料如下。
出处 《中华全科医师杂志》 2011年第4期281-282,共2页 Chinese Journal of General Practitioners
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参考文献9

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二级参考文献13

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共引文献8

同被引文献56

  • 1王晓川.X连锁无丙种球蛋白血症的临床特点[J].中华儿科杂志,2004,42(8):564-567. 被引量:22
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  • 3应大明 王晓川 杨锡强 等.原发性免疫缺陷病的协作网和登记工作[J].中华儿科杂志,1999,37:328-329.
  • 4Samuels J, Ng YS, Coupillaud C, et al. Human B cell tolerance and its failure in rheumatoid arthritis[J]. Ann N Y Acad Sci, 2005,1 062:116-126.
  • 5Tsukada S, Saffran DC, Rawlings DJ, et al. Deficient expression of a B cell cytoplasmic tyrosine kinase in hu- man X linked agammaglobulinemia [J]. Cell, 1993, 72 (2) :279-290.
  • 6Conley ME, Notarangelo LD, Etzioni A. Diagnostic criteria for primary immunodeficiencies. Representing PAGID (Pan-American Group for Immunodeficiency) and ESID (European Society for Immunodeficiencies) [J]. Clin Immunol, 1999,93(3) :190-197.
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