C反应蛋白、白细胞及中性粒细胞比例检测相关性分析

Study on correlation among different levels of CRP,WBC count and percentage of neutrophils.

目的探讨不同浓度的C反应蛋白(CRP)、白细胞(WBC)、中性粒细胞(NEU)比例(N%)值之间的关系。方法对90例感染性疾病患者及90例正常对照组进行CRP、WBC、中性粒细胞比例值检查。结果 CRP高浓度(CRP>50 mg/L)的感染组,以及各感染组CRP、NEU比例值与对照组比较均有显著性差异(P<0.01);CRP低浓度(10 mg/L)<CRP<50 mg/L)的感染组的WBC与对照组比较无明显差异(P>0.05);各感染组WBC正常例数,及各感染组CRP、WBC、NEU比例值上升例数与对照组比较均有差异(P<0.05)。各感染组WBC下降例数与对照组比较均无明显差异(P>0.05)。CRP与WBC、NEU比例值呈一定的正相关。CRP低浓度(10 mg/L)<CRP<50 mg/L)的感染组WBC正常率大于上升率,与CRP高浓度(CRP>50 mg/L)的各感染组相反。结论 在感染情况下,特别是感染程度较轻时,CRP检测优于WBC、NEU比例值,三者结合检查有助于提高感染性疾病诊断和治疗。

Objective To study the relationship among different levels of CRP,WBC count and neutrophil percentage.Methods Serum levels of CRP,WBC count and percentage of neutrophils were determined in 90 cases with infection,and 90 normal persons were selected for control.Results There was significant difference in WBC count and neutrophil percentage between patients with high level of CRP（CRP50） group,various infection group and control group（P0.01）,and there was no difference in patients with low level of CRP（P0.05）.CRP and WBC,NEU was a certain percentage of the value of a positive correlation.Conclusion Examination of serum level of CRP is better than determination of WBC count and N% in patients with infection,especially in low level of infection.Detection of them can be helpful in diagnosis and treatment of infectious diseases.