脉图参数评估抑郁症患者植物神经功能特点的探索性研究

Exploratory Research on Pulse Parameters Assessment on Autonomic Nervous Function of Depression

目的研究抑郁症患者植物神经功能参数变化的特点,为抑郁症临床诊断及辨证治疗提供相应的指导,并为脉诊的客观化研究提供新思路和方法。方法将100例抑郁症患者分为肝郁气滞组、肝(气)郁化火组、肝郁脾虚组、气阴两虚组、肝肾阴虚组、痰气互郁组,采用脉象仪DDMX-100(上海中医药大学自主研制)对抑郁症患者及44例正常对照组进行脉图测试,采集患者桡动脉(寸口)的脉象信息,并运用脉图参数评估抑郁症患者植物神经功能,分析其变化特点和规律。结果抑郁症患者PHZS(Vh/Vt)值升高,且各组PHZS值均高于正常组;痰气互郁组Vt值降低;肝郁脾虚组Vh值高于正常对照组和痰气互郁组。结论脉图参数和植物神经功能参数可作为抑郁症的诊断和辨证指标。

Objective To discuss the parameters of autonomic nervous fianction of depression, so as to instruct the diagnosis and syndrome differentiation of depression, and provide new ideas and methods for objectification study of pulse diagnosis. Method One hundred depression patients were divided into six groups： Stagnation of liver-qi, liver depression transforming into fire, liver stagnation and spleen deficiency, qi-yin deficiency, yin deficiency of liver and kidney, intermingled phlegm and qi. The feature and discipline of autonomic nervous function in each group were analyzed by collecting the pulse condition of depression patients with DDMX-100 electro-pulsograph （independently developed by Shanghai University of TCM）, with 44 normal people as control Result The parameter PHZS in depression patients was higher than normal control group, and so was each group of depression. The parameter Vt of intermingled phiegm and qi group was lower than that of normal control group. The parameter Vh of liver stagnation and spleen deficiency group was higher than that both intermingled phlegm and qi group and normal control group. Conclusion Pulse parameters and the autonomic nervous function parameters may be used as one of the indexes in diagnosis and syndrome differentiation in depression.