正交试验优选胃瘤消颗粒的提取工艺

Optimization of Extraction Process of Weiliuxiao Granules by Orthogonal Test

目的优选胃瘤消颗粒的提取工艺。方法采用正交试验法,以加水量、提取时间、提取次数作为考察因素,以有效成分黄芪甲苷、补骨脂素与异补骨脂素的含量为考察指标,对提取工艺进行筛选。结果最佳提取工艺为加14倍量水,超声提取3次,每次0.5 h。结论经正交试验设计优化的提取工艺合理可行。

Objective To optimize the extraction process of Weiliumao granules. Methods With the cotents of astragaloside, psoralen and isopsoralen as the indexes, the amount of water, the extracting time and the number of times as the factors, orthogonal test was employed for selecting the optimum extraction process Results The best extraction process was that adding 14 times of water, extracting 0.5 h and three times. Conclusion The extraction process selected by orthogonal test is reasonable and favorable for industrial production.