手法针刺合谷穴得气与脑功能激活关系的探讨

Observation of the relation between brain activity and de qi sensation with manual acupuncture at LI4 (Hegu)

目的探讨针灸"得气"与脑功能激活的关系。方法 13例健康右利手受试者,由针灸医师先后进行右手合谷穴"浅表刺激"与传统手法捻针刺激两种任务,利用fMRI-BOLD技术获得脑功能图像,用感兴趣区(ROI)分析方法,比较两种任务下的平均信号变化情况。结果针灸"得气"存在个体差异,相应脑功能的激活情况也有所不同,前额区、丘脑、纹状体、扣带回后部及岛叶功能区随着得气强度的增加而有激活明显的趋势。结论手法针刺合谷穴引起脑功能激活的程度与"得气"情况有关。

Objective：To discuss the relation between brain activity and de qi sensation with manual acupuncture.Materials and Methods：Manual acupuncture and superficial tactile stimulations were successively performed on 13 right handed healthy volunteers.Brain mappings were obtained with BOLD-based fMRI technique,and the brain regions activated during two stimulations were analyzed.Results：During manual acupuncture,all volunteers developed different de qi sensation,and the brain activity was individual different correspondingly.The activity of anterior frontal region,thalamus,Corpus striatum,Posterior cingulate cortex,and insula induced by acupuncture at acupoint LI4 （Hegu） had the trend of increasing with acupuncture intensities.Conclusion：There are some relationship between acupuncture intensities （de qi sensation） and brain activity evoked by acupuncture.