强迫症患者表演心理剧的临床疗效与性别的关系探讨

Investigate the relation for the effection of the patients of obsessive-compulsive disorder were treated by psychology-play and sex

目的:了解强迫症患者表演心理剧的临床疗效与性别的关系。方法:对我院2009年3月至2010年2月门诊治疗的强迫症患者中随机抽取男、女各80名,分成观察组和对照组,观察组年龄16～35岁(23.73±4.01),对照组年龄17～33岁(23.87±3.97),两组年龄无明显差异(P>0.05)。观察组给予药物帕罗西汀片(浙江华海)20～40 mg/d,联合心理剧疗法,每周1次,连续观察6周;对照组只接受药物帕罗西汀片(浙江华海)20～40 mg/d。选择Yale-Brown强迫症状量表于治疗前,治疗第2周末、第4周末及第6周末分别进行测试,两组进行比较(x±s),并确定有效为Yale-Brown强迫症状量表评分≤10分;于治疗第6周末对观察组进行x2检验,了解临床疗效与性别的关系。结果:于治疗前及治疗第2、4、6周末进行Yale-Brown强迫症状量表测试,两组结果(观察组:28.81±4.02、22.28±5.57、16.08±2.06、8.44±1.31;对照组:29.55±3.33、23.13±1.79、21.41±2.33、18.81±2.56)比较,治疗前及治疗第2周末,两组评分无明显差异(P>0.05),第4周末和第6周末两组比较均有显著差异(P<0.01);于治疗第6周末对观察组的疗效与性别进行x2检测,结果显示:女性的疗效优于男性(x2=8.79,P<0.01)。结论:强迫症患者应用药物联合心理剧的疗效优于单独药物治疗;临床疗效与性别有关,女性患者的疗效优于男性。

Objective：To explore the relation for the effection of the patients of obsessive-compulsive disorder were treated by psychology-play and sex.Methods：160 patients of obsessive-compulsive disorder were treated at clinic from March in 2009 to February in 2010,they were divied into study group and control group,study group were treated for six weeks with payoxetine tablets（Huahai Zhejiang） plus psychology-play once a week.While control group was treated with Payoxetine tables only.In study group,their ages are from sixteen to thirtr-five（23.73±4.01）;In control group,their ages are from seventeen to thirty-three（23.87±3.97）.There was no significant difference between the two groups ages（P〉0.05）.Yale-Brown Compel Symptom Test was administered before the treatment and at the end of second week and at the end of Forth week and at the end of sixth week,efficiency score don′t exceed 10,and compare two groups（-x±s）,and at the end x^2 test was administed for assessing the relation for the effection and sex.Results： Yale-Brown Compel Symptom Test was administered before the treatment and at the end of second week and at the end of forth week and at the end of sixth week,the results（study group：28.81±4.02 22.28±5.57 16.08±2.06 8.44±1.31;control group：29.55±3.33 23.13±1.79 21.41±2.33 18.81±2.56） were compared,before the treatment and at the end of second week,two groups scores were no significant difference（P〉0.05）;and at the end of forth week and at the end of sixth week,study group scores were lower than control group（P〈0.01）;at the end of sixth week in study group x^2 test was administered for assessing the relation of the effect and sex（mankind,female）,the effect of female patients were better（x^2=8.79,P〈0.01）.Conclusions： The effect of the patients of obsessive-compulsive disorder were treated with Paroxetin tablets plus Psychology-play was better than Paroxetin tablets only;for the effect and sex（mankind,female）,they have more relation,the effect of female patients of obsessive-compulsive disorder is better