QT离散度与高血压左室肥厚的相关性研究

Study on the Relationship between QT Dispersion and Left Ventricular Hypertrophy in Hypertension

目的探讨QT离散度与高血压左室肥厚的关系及其对临床的指导意义。方法根据12导联常规心电图和超声心动图监测结果将90例原发性高血压(EH)患者分为伴左室肥厚者(LVH组)50例和不伴左室肥厚者(非LVH组)40例,比较两组患者的QT离散度(QTd)和左室重量指数(LVMI)。结果两组病人QT离散度LVH组为(65.14±7.47)ms,NLVH组为(37.86±6.98)ms,经统计学处理差异有统计学意义(P<0.05),说明高血压伴左室肥厚组病人QTd明显增大。左室心肌重量和左室肌质量指数比较LVH组明显高于NLVH组(P<0.05)。结论 QTd是反映心室肌复极的不均匀性指标,是一种无创、简便预测高血压合并左室肥厚预后有价值的指标,可为严重心律失常的发生提供有利的治疗和预防措施。

Objective To evaluate the relationship between QT dispersion and left ventricular hypertrophy in hypertension and its clinical significance.Methods According to the conventional 12-lead ECG and echocardiography results,90 patients with essential hypertension（EH）were divided into two groups,50 patients with left ventricular hypertrophy（LVH group）and 40 patients without left ventricular hypertrophy（non-LVH group）,QT dispersion（QTd）and left ventricular mass index（LVMI）were compared in the two groups.Results QT dispersion in LVH group was（65.14±7.47）ms,and in NLVH group was（37.86±6.98）ms,the difference was statistically significant（P〈0.05）.QTd was significantly larger in the patients with hypertension and left ventricular hypertrophy.Left ventricular mass and left ventricular muscle mass index of LVH group was significantly higher than that of NLVH group（P〈0.05）.Conclusion QTd is an index of ventricular repolarization heterogeneity,is a noninvasive,simple,valuable indicator to predict hypertension and left ventricular hypertrophy,and may be provided treatment and prevention measures for the occurrence of severe arrhythmia.