2007—2009年成都地区17家医院抗感染药应用分析

Utilization of Anti-infective Drugs in 17 Hospitals of Chengdu Area from 2007 to 2009

目的:了解2007—2009年成都地区17家医院抗感染药的应用情况。方法:以销售金额、用药频度(DDDs)等对2007—2009年成都地区17家医院抗感染药进行分类统计、综合分析、对比。结果:3年间年成都地区17家医院抗感染药用药金额增长幅度较大,各亚类抗感染药中头孢菌素类、化学合成药、青霉素类用药金额排序依次占前3位,抗病毒、抗真菌药使用增多,氟喹诺酮类药物限制性使用。销售金额及用药频度前10位中,大多数是β-内酰胺酶抑制剂。结论:抗菌药物的细菌耐药率增长迅速,二重感染现象加剧,需加强抗感染药的合理应用和规范化管理。

OBJECTIVE：To investigate the utilization status of anti-infective drugs in 17 hospitals of Chengdu from 2007 to 2009.METHODS：The anti-infective drugs used in 17 hospitals of Chengdu from 2007 to 2009 were subjected to classified statistic,aggregate analysis and comparison in respect of the consumption sum and DDDs.RESULTS：The consumption sum of anti-infective drugs in 17 hospitals of Chengdu during 3 years witnessed a significant increase,with cephalosporins,chemical synthetic drugs and penicillins leading the first three places in order.The consumption of antifungal drugs increased while the use of quinolone antibiotics was restricted.The majority of the drugs which ranked in the first 10 places in terms of consumption sum or DDDs were β-lactamase inhibitors.CONCLUSION：Rational use and standardized administration of anti-infective drugs remain to be strengthened in view of the rapid increased antibiotic resistance rates of anti-infective drugs and the worsening dual infection.