摘要
目的:了解我院药品不良反应(ADR)发生情况及相关因素,促进我院合理用药。方法:对我院2008年4月—2009年12月收集的445例ADR报告进行统计、分析。结果:445例ADR报告共涉及134种药品,静脉滴注是引起ADR的主要给药途径(84.49%);抗微生物药发生ADR最高(47.19%);中药注射剂引起的ADR在所有中药制剂中最多(82.35%);临床表现主要为皮肤及其附件损害(17.08%)。结论:加强ADR监测,减少或避免ADR的发生。
OBJECTIVE:To investigate the status and the related factors of the adverse drug reactions(ADRs) occurred in our hospital to promote the rational drug use our hospital.METHODS:A total of 445 ADR case reports collected in our hospital from Apr.2008 to Dec.2009 were analyzed statistically.RESULTS:Of the 445 ADR reports,134 kinds of drugs were involved.Intravenous drip infusion was the major route of administration(84.49%) in the ADR cases;the ADR was chiefly induced by antimicrobial agents(47.19%).Of all the ADR cases induced by Chinese drugs pharmaceutics,traditional Chinese medicinal injectable preparation took the lead(82.35%).The main clinical manifestation of the ADRs included lesion of skin and its appendants(17.08%).CONCLUSION:ADR monitoring should be strengthened to reduce or avoid its occurrence.
出处
《中国医院用药评价与分析》
2011年第3期265-268,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
报告
分析
合理用药
Adverse drug reaction(ADR)
Report
Analysis
Rational drug use