脑胶质瘤颅外转移一例并文献复习

One case of extracranial metastasis of glioma and literature review

目的 探讨脑胶质瘤颅外转移的可能机制和临床特点.方法 报道一例最近诊治的具有完整临床和病理证据的脑胶质瘤颅外转移患者.结果 脑胶质瘤颅外转移较为罕见,本例患者胸部X线片可见双肺多发转移瘤,胸部CT示多发大小不等的结节软组织肿物影,诊断为脑胶质瘤颅外转移.结论 脑胶质瘤颅外转移的转移路径及机制尚不能明确,多路径机制可能较为合理.开放式的肿瘤切除术可能有助于延长患者的生存时间,但也不排除增加颅外转移的可能.

Objective To explore the mechanisms and clinical characteristics of neuroglioma that was complicated with extracranial metastases. Methods A newly-diagnosed neuroglioma case in our department was reported with completely clinical and pathological data to discuss the extracranial metastases. Meanwhile the domestic and abroad literature were reviewed. Results The extracranial metastasis of glioma was rare. In this cases, X-ray chest displayed multiple metastatic tumors, and CT of chest showed nodules soft tissue mass shadows varied in size. Accordingly the diagnosis was neuroglioma complicated with extracranial metastases. Conclusions The transferring paths and mechanisms are ambiguous. Tumor resections may be helpful in prolonging the survival time and in increasing the potential of the tumor transferring from intracranial to extracranial.