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布地奈德联合特布他林雾化吸入治疗哮喘急性发作 被引量:13

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摘要 目的探讨布地奈德联合特布他林雾化吸入治疗哮喘急性发作的疗效及安全性。方法将64例哮喘急性发作患者随机分为治疗组和对照组;两组患者常规予以吸氧、抗感染、静滴氨茶碱、止咳化痰等对症治疗。治疗组在此基础上加用布地奈德混悬液2mL/次联合特布他林雾化液2mL/次雾化吸入,每天2次,连用1周;对照组单用布地奈德混悬液,剂量和次数同治疗组。结果治疗组患者在喘憋、咳嗽、哮鸣音和湿啰音消失时间方面明显优于对照组(P<0.05),治疗组的临床总有效率明显高于对照组(P<0.05)。两组患者治疗1周后的肺功能指标FEV1、FEV1/FVC和PEF均较治疗前明显改善(P<0.05或P<0.01),且治疗组改善幅度较对照组更明显(P<0.05),两组治疗期间无严重不良反应。结论布地奈德联合特布他林雾化吸入治疗哮喘急性发作的临床疗效确切,能明显改善患者的肺功能,安全性较好。
作者 金标
出处 《中国现代医生》 2011年第8期126-127,共2页 China Modern Doctor
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