摘要
1例56岁男性患者,因脑外伤静脉输注单唾液酸四己糖神经节苷脂(100 mg·L-1,qd),7 d后出现四肢无力,心慌、胸闷;翌日,四肢无力加重,腱反射消失,不能行走。肌电图检查并经上级医院专家会诊确诊为格林-巴利综合征。治疗方案:大剂量甲强龙冲击治疗(500 mg×3 d,240 mg×3 d,120 mg×3 d),再调整为口服强的松。辅以人血免疫球蛋白(27.5 g,qd,ivgtt),连用5 d。甲钴胺1 mg静推。6周后病人好转,能自行站立。
A 56-year-old male was given an intravenous infusion of ganglioside injection 100 mg·L-1 once daily in the treatment of brain injury.After 7 days,he developed myasthenia of limbs,fluster,chest tightness.In the following day,myasthenia of limbs became severer and tendon-reflex disappeared,which was diagnosed as Guillain-Barré syndrome according to the electromyogram and experts consultation.The patient was treated with corticosteroids injection（500 mg×3 d,240 mg×3 d,120 mg×3 d） and then oral administration of prednisone instead.Six weeks later,the patient got improvement.
出处
《中国药物应用与监测》
CAS
2011年第2期129-130,共2页
Chinese Journal of Drug Application and Monitoring
