慢心律联合丹参治疗糖尿病周围神经病变的疗效观察

INJECTION OF DANSHEN AND MEXILETINE IN THE TREATMENT OF DIABETIC PERIPHERAL NEUROPATHY

目的 :为糖尿病周围神经病变探讨有效的治疗方法。方法 :选择 65例糖尿病周围神经病变患者 ,随机分为两组 ,一组为慢心律治疗组 ,另一组为慢心律联合丹参注射液治疗组 ,以临床表现改善客观指标及运动传导速度 (MCV)、感觉传导速度 (SCV)测定做为判定标准。结果 :两组经治疗 4wk后 ,慢心律组总有效率为76 7% ,慢心律联合丹参注射液组总有效率为 94 3 %。两组肌电图显示神经传导异常率均下降 ,而以慢心律联合丹参注射液组作用较强 (P <0 0 5 )。结论

Objective: To study effectual remedy for diabetic patients with peripheral neuropathy. Methods:65 diabetic patients with peripheral neuropathy were selected and randomly divided into injection of danshen and mexiletine group ( n= 35) and simple mexiletine group ( n= 30). The conditon of diabetic patients with peripheral neuropathy was dicided by clinical picture and motor conduction velocity (MCV), sensory conduction velocity(SCV). Results: After treatment for 4 weeks, effectual rate of mexiletine group is 76.7%, effectual rate of mexiletine and injection of danshen group is 94.3%. Conclusion:A significant differences were observed that injection of danshen and mexiletine group was more efficient than mexiletine group in the treatment of diabetic peripheral neuropathy.