莫西沙星治疗脑血管病伴吸入性肺炎的临床观察

Clinical Observation of Moxifloxacin in the Treatment of Cerebrovascular Disease Complicating with Aspiration Pneumonia

目的:观察莫西沙星治疗脑血管病伴吸入性肺炎患者的有效性和安全性。方法:选择112例脑血管病伴吸入性肺炎患者,应用莫西沙星(0.4g,qd,静脉滴注)治疗,观察其临床疗效、安全性。结果:莫西沙星治疗脑血管病患者吸入性肺炎有效率为86%,痊愈率为55%,细菌清除率为77%,不良反应发生率为7%。结论:莫西沙星治疗脑血管病伴吸入性肺炎效果好,不良反应少。

OBJECTIVE：To evaluate the efficacy and safety of moxifloxacin in the treatment of cerebrovascular disease complicating with aspiration pneumonia.METHODS：112 patients with cerebrovascular disease complicating with aspiration pneumonia who were treated with moxifloxacin（0.4 g,qd,iv.gtt） were enrolled in this study.The clinical efficacy and safety were analyzed.RESULTS：The effective rate and curative rate of moxifloxacin therapy were 86% and 55%,respectively.The bacterial eradication rate was 77%,and the rate of adverse drug reaction was 7%.CONCLUSION：Moxifloxacin therapy is effective in the treatment of cerebrovascular disease complicating with aspiration pneumonia with few adverse drug reaction.