2004-2010年龙游县肾综合征出血热监测结果分析

Analysis on the surveillance results of hemorrhagic fever with renal syndrome in Longyou county of Zhejiang province from 2004 to 2010

目的通过监测结果分析,掌握龙游县肾综合征出血热(HFRS)流行规律,有针对性地采取防控措施。方法对2004-2010年HFRS疫情资料进行分析,并采用现场调查与实验室检测相结合,开展人间疫情与宿主动物带病毒监测。结果龙游县2004-2010年HFRS年平均发病率为0.78/10万,患者以40～50岁为主,占63.64%,农民占77.27%,男女比例为2.14:1。季节高峰呈夏季和冬季的双峰型,全县多个乡(镇)均有发病,以龙南山区发病率最高。患者诊断符合率为82.35%。鼠类带病毒率为2.95%,室内以黄胸鼠为优势种,占80.28%;室外以黑线姬鼠为优势种,占89.29%。鼠血清HFRS抗体阳性率为4.81%。结论龙游县HFRS发病率呈现下降趋势,但流行特征并未发生明显改变。监测结果显示,龙游县是以姬鼠型为主的混合型HFRS疫区。

Objective To determine the epidemiological characteristics of hemorrhagic fever with renal syndrome（HFRS） in Longyou county based on analysis of surveillance results for the deployment of specific control measures.Methods HFRS surveillance data from 2004 to 2010 were analyzed in combination with field investigation and laboratory tests to reveal the virus distribution in human and host animals.Results The average annual incidence rate was 0.78/105 from 2004 to 2010 in Longyou county.Most patients were at the age from 40 to 50 years,accounting for 63.64%.Farmers accounted for 77.27% of all patients.The ratio of male to female was 2.14：1.Summer and winter were two incidence peak periods in a year.The onset cases were observed in most of towns and villages.The highest incidence was found in Longnan mountain area.The diagnosis accuracy was 82.35%.The virus-carrying rate was 2.95% in rodents with Rattus tanezumi being the predominant host animal indoor（80.28%） and Apodemus agrarians being the predominant host outdoor（89.29%）.The seroprevalence of HFRS antibodies in rats was 4.81%.Conclusion A declining trend of the HFRS incidence is shown in Longyou county,though the epidemiological characteristics of this disease remain unchanged.The surveillance results have shown that Longyou county is a mixed HFRS epidemic area dominated by the Apodemus type.