医院内鲍曼不动杆菌感染调查及泛耐药情况分析

Analysis on the infection and extensive drug-resistance of Acinetobacter baumannii in hospital

目的:了解某院近3年来医院内鲍曼不动杆菌感染现状,分析其耐药谱变迁及泛耐药情况,为临床了解及防控院内感染提供依据。方法:对医院2007年-2009年分离的鲍曼不动杆菌分布及耐药情况进行回顾性分析。细菌鉴定采用美国德灵细菌鉴定仪。结果:3年间共分离到鲍曼不动杆菌305株,其中2007年72株2,008年91株,2009年142株,其中通过呼吸道感染占82.12%。泛耐药菌株感染率呈现出逐年上升趋势,2007年5株(占6.94%)2,008年9株(占9.89%)2,009年有19株(占13.38%)。结论:鲍曼不动杆菌感染呈逐年上升趋势,以呼吸道感染方式为主,其泛耐药菌株感染率呈上升趋势。应加强病房环境和人员消毒,加强抗生素的合理使用,控制鲍曼不动杆菌在医院内的定值和播散,重视泛耐药鲍曼不动杆菌监测。

Objective：To study the infection situation of Acinetobacter baumannii in Yuebei hospital in the past three years,analyze the transition and status of extensive drug-resistance,provide the evidence for clinical study and the prevention of hospital infection.Methods：A retrospective analysis for the distribution and drug-resistance of Acinetobacter baumannii from 2007-2009.Bacteria were identified by identification instrument from America.Results：305 Acinetobacter baumannii were isolated in the past three years,among which 72 strains from 2007,91strains from 2008,142 strains from 2009,and totally 82.12% were infected by respiratory tract.The infection rate of pandrug-resistance strain rose year by year,among which 5 strains in 2007（6.94%）,9 strains in 2008（9.89%）,19 strains in 2009（13.38%）.Conclusion：It showed a rising trend of the infection of Acinetobacter baumannii,the main infection way was respiratory tract and the infection rate of pandrug-resistance strain rose year by year.As such,it is suggested to strengthen the ward and personal decontamination,use the antibiotics properly,control the set value and dissemination of Acinetobacter baumannii in hospital,and take surveillance of pandrug-resistance of Acinetobacter baumannii seriously.