灰毡毛忍冬茎叶化学成分研究

Studies on the Chemical Constituents from Stems and Leaves of Lonicera macranthoides

目的:对灰毡毛忍冬茎叶化学成分进行研究。方法:利用各种色谱技术进行分离,根据化合物的光谱数据(IR、MS1、H-NMR1、3C-NMR)和化学方法鉴定其结构。结果:从灰毡毛忍冬茎叶中分离得到9个化合物,分别鉴定为:马钱子苷(Ⅰ)、马钱子苷酸(Ⅱ)、莫罗忍冬苷(Ⅲ)7、-O-乙基莫罗忍冬苷(Ⅳ)、东莨菪素(Ⅴ)、咖啡酸(Ⅵ)、绿原酸(Ⅶ)、β-谷甾醇(Ⅷ)、胡萝卜苷(Ⅸ)。结论:化合物Ⅰ～Ⅵ为首次从该植物中分离得到,所有化合物均是首次从该植物茎叶中分离得到。

Objective：To research the chemical constituents from stems and leaves of Lonicera macranthoides.Methods：Various column chromatographies were employed to isolate and purify the constituents.Their structures were elucidated by spectral analysis（IR,MS,1H-NMR,13C-NMR）and chemical evidence.Results：Nine constituents were obtained and identified as loganin（Ⅰ）,loganic acid（Ⅱ）,morroniside（Ⅲ）,7-O-ethyl-morroniside（Ⅳ）,scopoletin（Ⅴ）,caffeic acid（Ⅵ）,chlorogenic acid（Ⅶ）,β-sitosterol（Ⅷ）,daucosterol（Ⅸ）.Conclusion：CompoundsⅠ~Ⅵ are isolated from the plant for the first time.All the compounds are found for the first time from the stems and leaves of Lonicera macranthoides.