毛泡桐叶化学成分研究

Studies on the Chemical Constituents from the Leave of Paulownia tomentosa

目的:对毛泡桐叶的化学成分进行分离与鉴定。方法:利用硅胶色谱柱层析进行分离纯化,通过波谱分析鉴定其结构。结果:从毛泡桐叶的乙酸乙酯部分分离得到10个化合物,分别鉴定为:洋芹素(Ⅰ)、木樨草素(Ⅱ)、高北美圣草素(Ⅲ)、3α-羟基-乌苏酸(Ⅳ)、19α-羟基-乌苏酸(坡模酸)(Ⅴ)、2α,3α-二羟基-12烯-28-乌苏酸(Ⅵ)、乌苏酸(Ⅶ)2、α-羟基-齐墩果酸(山楂酸)(Ⅷ)、胡萝卜苷(Ⅸ)、β-谷甾醇(Ⅹ)。结论:化合物Ⅰ～Ⅹ为首次从毛泡桐叶中分离得到。

Objective：To study the chemical constituents of the leave of Paulownia tomentosa.Methods：The constituents were isolated by column chromatography and their struc-tures were elucidated through spectroscopic analysis.Results：The compounds were identified as apigenin（Ⅰ）,uteolin（Ⅱ）,homoeriodictyol（Ⅲ）,3α-hydroxyurs-12-en-28-oic acid（Ⅳ）,3β,19α-dihydroxyurs-12en-28-oic acid（pomolic acid）（Ⅴ）,2α,3α-dihydroxyurs-12-en-28-oic acid（Ⅵ）,ursolic acid（Ⅶ）,2α,3β-dihydroxyolean-12-en-28-oic acid（maslinic acid）（Ⅷ）,daucosterol（Ⅸ）,β-sitosterol（Ⅹ）.Conclusion：The compoundⅠ～Ⅹare obtained from the leave of Paulownia tomentosa（Thunb.）Steud for the first time.