绝经前后妇女骨密度测定

Analysis of BMD in Premenopause and Postmenopause

目的研究妇女绝经后骨质疏松与雌激素的关系。方法收集了２５５例年龄在３２～７３岁之间的绝经前后的妇女。分成４组：月经正常、月经紊乱、自然绝经和人工绝经（双侧卵巢切除术）。用双能Ｘ线骨密度测定仪进行测量。结果妇女月经紊乱后，骨密度就明显下降，而绝经后的５年内显著下降。手术切除卵巢后，５年内骨密度也显著下降。结论绝经前切除卵巢或过早的闭经易导致骨质疏松，即妇女绝经后骨质疏松与雌激素下降有显著关系（Ｐ＜０．００１）。

Purpose To study the relationship between osteoporosis of postmenopausal women and leads of estrogen.Methods Two hundred fifty five premenopausal and postmenopausal women aged 32 to 73 were divided in to four groups,i.e,normal menstruation,irregular menstruation,natural menopause and artificial menopause(bilateral ovariotomy).Bone mineral density(BMD) data of these women were collected by dual energy X ray absorptiomtry bone densitometer in our hospital. Results BMD is markedly decreased at the beginning of irregular menstruation,and particularly within the next five years.As a result of ovariotomy,BMD markedly dec reased in the following five years. Conclusions Ovariotomy before menopause or previous menoschesis will cause osteoporosis.Essentially,the falling level of estrogen in women is significantly related to osteoporosis. ( P <0.001) .