2010年邹城市部分人群甲型H1N1流感血清抗体水平调查

Investigation on Influenza Type A(H1N1) Antibody Level in the Population of Zoucheng City,2010

[目的]了解人群甲型H1N1流感（甲流）病毒抗体水平,掌握接种甲流疫苗后的抗体水平增长情况。[方法]2010年1月和4月,在邹城市抽取6个镇,对部分人群采血,检测血清甲流病毒抗体。[结果]2次调查合计检测1 500人,甲流病毒抗体阳性的404人,阳性率为26.93%。甲流病毒抗体阳性率,1月为31.73%,4月为22.13%（P〈0.01）;男性为29.39%,女性为24.97%（P〉0.05）;0-5岁、6-15岁、16-24岁、25-59岁、≥60岁分别为22.67%、48.33%、36.67%、14.00%、13.00%（P〈0.01）;峄山镇、大束镇、北宿镇、城前镇、看庄镇、太平镇分别为40.80%、26.40%、40.80%、30.40%、21.20%、14.80%（P〈0.01）;接种过甲流疫苗者为79.63%,未接种者为22.84%（P〈0.01）。[结论]人群中甲流免疫屏障尚未建立,目前仍需加强流感疫苗接种。

[Objective]To explore antibody level against influenza A（H1N1） virus in the people,understand the growing of antibody level after the vaccination of H1N1 vaccine.[Methods]Blood samples were collected in 6 towns in Zoucheng in January and April,2010.The samples were tested for influenza A virus antibody.[Results]Of the 1 500 people investigated,404 of them were positive for influenza A virus antibody,accounting for 26.93%.The positive rate was 31.73% and 22.13% in January and April（P0.01）,29.39% and 24.97% in male and female（P0.05）,22.67%,48.33%,36.67%,14.00% and 13.00% in the people aged from 0 to 5,6 to 15,16 to 24,25 to 59 and over 60 respectively（P0.01）.It was 40.80%,26.40%,40.80%,30.40%,21.20% and 14.80% respectively（P0.01） in Yishan,Daishu,Beisu,Chengqian,Kanzhuang and Taiping towns.The positive rate was 79.63% and 22.84% in the people vaccinated and non-vaccinated（P0.01）.[Conclusion]Immunologic barrier was not established,vaccination with influenza vaccine should be strengthened.